Petr Cech returned to Chelsea in 2019
The former Blues goalkeeper took up the role in 2019, marking his return to Stamford Bridge.
The 40-year-old spent 11 years as a Chelsea player, winning 13 trophies, including four Premier League titles and the Champions League.
"It has been a huge privilege to perform this role at Chelsea for the past three years," he said.
"With the club under new ownership, I feel now is the right time for me to step aside.
"I am pleased that the club is now in an excellent position with the new owners and I am confident of its future success both on and off the pitch."
Cech is the latest person to leave Chelsea following the club's takeover by a consortium led by American businessman Todd Boehly.
Like Cech, chairman Bruce Buck will step down on 30 June - and last week Chelsea also confirmed the departure of director Marina Granovskaia.
-- Courtesy of BBC Sport